Piroctone Olamine (Kopirox) is known for its
bacteriostatic and fungistatic properties specifically working against
Pityrosporum ovale, which lives on the skin and is associated with dandruff and
other manifestations of flaking on the face and scalp. It is often used in
shampoo as a replacement of commonly used Zinc Pyrithione. It is used over 30
years in the personal care formulations and also used as preservative and
thickening agent.
Hair shedding and hair thinning have been
reported to be affected by dandruff and seborrheic dermatitis. In a comparative
clinical study, it was demonstrated that Piroctone Olamine outperformed
Ketoconazole and zinc pyrithione based shampoo in its ability to increase hair
shaft diameter in androgenic alopecia. Piroctone Olamine also reduced sebum
production.
Application:
Transparent antidandruff
shampoos
As a preservative and thickening agent in
cosmetic preparations.
In general hair care formulations and
used against seborrheic dermatitis.
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