Zinc Pyrithione was first reported in the
1930s. It has two pyridine-derived chelating ligands bound to zinc via oxygen
and sulfur atoms. In cosmetics and personal care products, Zinc Pyrithione
functions as an antidandruff agent, antimicrobial agent, hair conditioning
agent, and preservative.
Zinc pyrithione has been used, as an anti-dandruff
agent, for more than 60 years, in concentrations up to 1-2%. It is effective
against a wide variety of pathogenic bacteria. Its other applications include
treatments of psoriasis, eczema, ringworm, fungus, athletes’ foot, dry skin,
and atypical dermatitis Due to its low solubility in water, zinc pyrithione is
suitable for use in outdoor paints and other products that provide protection
against mildew and algae. Its decomposition by ultraviolet light is slow,
providing years of protection even against direct sunlight.Antifungal effect of
Zinc prithione is most likely lies in the ability of an un-ionized pyrithione
molecule to disrupt membrane transport by blocking the proton pump that
energizes the transport mechanism.
Application:
Antidandruff formulation, outdoor paint, coating agent for airconditioner
covers, sealants for bathrooms, pools,
windows and as cosmetic preservative.
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